Progesterone (1124)

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Category:

CPT Code:

84144

Test Type: 1.0 mL Serum Kit Based
Stability Time:

Stability

Refrigerated: 5 days

Reference Range:

Men:

Sex/Phase ng/mL
N/A <0.05-0.15

Women:

Sex/Phase Optimal
Follicular phase 0.06-0.89 ng/mL
Ovulation phase 0.12-12.0 ng/mL
Luteal phase 1.83-23.9 ng/mL
Postmenopause <0.05-0.13 ng/mL

Overview:

Progesterone is a steroid hormone secreted by the corpus luteum and placenta to promote normal sexual function and secondary sex characteristics in women, as well as to prepare the uterus for implantation of the fertilized ovum and to maintain pregnancy.

Methodology

Immunoassay – Competitive principle

Progesterone is used in the assessment of menopausal status and fertility diagnosis.1-4

  • High doses of biotin (> 5 mg/day) may interfere with assay results. Patient assumed to be refraining from biotin supplementation for at least 3 days prior to blood draw.

References:

  1. Bhasin S, Cunningham GR, Hayes FJ, et al. Testosterone therapy in men with androgen deficiency syndromes: Endocrine Society clinical practice guidelines. J Clin Endorcinol Metab. 2010;95(6):2536-2559.
  2. Santen RJ, Allred DC, Ardoin SP, et al. Postmenopausal hormone therapy: an Endocrine Society scientific statement. J Clin Endocrinol Metab. 2010;95(7 Suppl 1):s1-s66.
  3. Kopper NW, Gudeman J, Thompson DJ. Transdermal hormone therapy in postmenopausal women: a review of the metabolic eff ects and drug delivery technologies. Drug Des Devel Ther. 2008;2:193-202.
  4. Goodman N, Cobin RH. Reproductive disorders. In: Camacho PM, Gharib H, Sizemore GW, eds. Evidence-Based Endocrinology. 3rd ed. Philadelphia, PA: Lippincott Williams & Wilkins. 2012:190-228.

Collection Details:

Collection Instructions:

Preferred Specimen

1.0 mL serum (0.5 mL minimum) collected in serum separator tube (SST / Tiger Top)

Transport Temperature

Refrigerated (ship on frozen cold packs)

Stability

Refrigerated: 5 days