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Temperature |
Period |
---|---|
Room temperature |
14 days |
Refrigerated |
14 days |
Frozen |
19 days |
Freeze/thaw cycles |
Stable x3 |
0.4-2.5 µmol/mmol crt
Overview:
Diagnose cobalamin (vitamin B12) deficiency.
This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.
Matchar DB, Feussner JR, Millington DS, Wilkinson RH Jr, Watson DJ, Gale D. Isotope-dilution assay for urinary methylmalonic acid in the diagnosis of vitamin B12 deficiency. A prospective clinical evaluation. Ann Intern Med. 1987 May; 106(5):707-710. PubMed 3551712
Specker BL, Miller D, Norman EJ, Greene H, Hayes KC. Increased urinary methylmalonic acid excretion in breast-fed infants of vegetarian mothers and identification of an acceptable dietary source of vitamin B12.Am J Clin Nutr. 1988 Jan, 47(1):89-92. PubMed 3337042
Stabler SP, Marcell PD, Podell ER, Allen RH, Lindenbaum J. Assay of methylmalonic acid in the serum of patients with cobalamin deficiency using capillary gas chromatography-mass spectrometry. J Clin Invest. 1986 May, 77(5):1606-1612. PubMed 3700655
Collection Instructions:
Plastic urine container, no preservative.
Room temperature.
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