Interleukin-04 (IL-4), Serum

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Turnaround Time: 4 - 7 days
CPT Code:

83520

Test Type: 0.5 mL Serum
Stability Time:

Refrigerate; stable for 14 days. Stable at room temperature or frozen for 14 days. Freeze/thaw cycles x3.

Overview:

Interleukin 4 (IL-4) is a pleiotropic cytokine produced by activated T lymphocytes, CD3+ cells, NK-T cells, mast cells, eosinophils, and basophils.1 IL-4 has multiple immune response modulation functions on a variety of cell types. It is an important regulator of isotype switching, inducing IgE production in B lymphocytes. It is an important modulator of the differentiation of precursor T helper cells to the TH2 subset that mediates humoral immunity and modulates antibody production. In addition, IL-4 has also been shown to have antitumor activity both in vivo and in vitro.1

Results of this test are for research purposes only by the assay's manufacturer. The performance characteristics of this assay have not been established. Results should not be used as a diagnostic procedure without confirmation of the diagnosis by another medically established diagnostic product or procedure.

1. Okada H, Banchereau J, Lotze MT. Interleukin-4. In: Thomson AW, Lotze MT, eds. Cytokine Handbook. Vol 1, 4th ed. San Diego, Calif: Academic Press; 2003: 227-262.

Collection Details:

Collection Instructions:

Red-top tube or gel-barrier tube.

Separate serum from the cells. Transfer serum to a plastic transport tube.

Refrigerate; stable for 14 days. Stable at room temperature or frozen for 14 days. Freeze/thaw cycles x3.