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Overview:
Immunoglobulin G (IgG) antibodies to specific allergens have not been proved to be involved in pathogenesis of disease. The presence of IgG against otherwise innocuous antigens (such as foods) in serum simply indicates that the individual has been exposed to antigens that are recognized as foreign entities by the immune system. The presence of food-specific IgG alone cannot be taken as evidence of allergy or autoimmune disease and only indicates immunologic sensitization by the food in question (1). Consequently, the quantitative IgG test should only be ordered by specialists who recognize the limitations of the test.
Special Instructions: Values obtained with different assay methods should not be used interchangeably in serial testing. It is recommended that only one assay method be used consistently to monitor each patient's course of therapy.
Methodology: Thermo Fisher ImmunoCAP(R)
Collection Instructions:
Specimen: Serum
Volume: 0.3 mL
Minimum Volume: 0.1 mL
Container: Red-top tube or gel-barrier tube
Storage Requirements: Room Temperature
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