Estrone (E1)

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Category:

Turnaround Time: 3 - 5 days
CPT Code:

82679

Test Type: 1 mL Serum or plasma
Reference Range:

See table.1-2

Age (y)

Male (pg/mL)

Female (pg/mL)

Tanner Stage I

5−17

4−29

Tanner Stage II

10−25

10−33

Tanner Stage III

15−25

15−43

Tanner Stage IV

15−45

16−77

Tanner Stage V

20−45

29−105

Adults

15−65

Follicular phase: 39−132

Periovulatory: 58−256

Luteal phase: 54−179

Pregnancy

1st trimester: 247−2774

2nd trimester: 569−5781

Postmenopausal

with ERT: 51−488

without ERT: 31−100

Overview:

Evaluate postmenopausal vaginal bleeding due to peripheral conversion of androgenic steroids. Increased estrone levels may be associated with increased levels of circulating androgens and their subsequent peripheral conversion.

1. Tietz NW, ed. Clinical Guide to Laboratory Tests. 4th ed. Philadelphia, Pa: WB Saunders Co; 2006:378-379.

2. Estrone RIA DSL8700-FOC-02 [package insert]. Beckman Coulter/ImmunoTech; 2018.

Kronenberg H, Williams HR. The physiology and pathology of the female reporductive axis. In: Williams Textbook of Endocrinology. 11th ed. Philadelphia, Pa: Saunders/Elsevier; 2008:541-614.

Gruber CJ, Tschugguel W, Schneeberger C, Huber JC. Production and actions of estrogens. N Engl J Med. 2002 Jan 31;346(5):340-352. PubMed 11821512

Collection Details:

Patient Preparation:

No isotopes administered 24 hours prior to venipuncture.

Collection Instructions:

Nonpregnant patients only.

Red-top tube, gel-barrier tube, or lavender-top (EDTA) tube.

If a red-top tube or lavender-top tube is used, transfer separated serum or plasma to a plastic transport tube.

Refrigerate.