Deaminated Gliadin Antibodies, IgA and IgG

Detection of gliadin antibodies aids in the diagnosis and monitoring of certain gluten-sensitive enteropathies, such as celiac disease and dermatitis herpetiformis A negative IgA result in an untreated patient does not rule out gluten-sensitive enteropathies, especially when associated with IgG gliadin antibodies. This can be explained by selective IgA deficiency, a relatively frequent finding in celiac disease. False-positives are possible as other gastrointestinal disorders are known to induce circulating antigliadin antibody, mainly Crohn disease, food protein intolerance, and postinfection malabsorption.

Component(s)

Panel/Test

Reflex Conditions

Test:

161652 Deamidated Gliadin Abs, IgA

Test:

161693 Deamidated Gliadin Abs, IgG

The patient should remain seated and not smoke throughout the test. Patient needs to have fasted 12 hours prior to test.