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Register NowCystatin C
Create a Free Account to View PricesTurnaround Time: 2 - 5 days
CPT Code:
82610
Test Type: 1 mL Serum or plasma
Stability Time:
|
Temperature |
Period |
|---|---|
|
Room temperature |
14 days |
|
Refrigerated |
14 days |
|
Frozen |
14 days |
|
Freeze/thaw cycles |
Stable x3 |
Reference Range:
0.62-1.16 mg/L
Overview:
Since it is formed at a constant rate and freely filtered by the healthy kidney, cystatin C is a good marker of renal function. Serum concentrations of cystatin C are almost totally dependent on glomerular filtration rate (GFR).1,2 A reduction in GFR causes a rise in the concentration of cystatin C.
Cystatin C has not been shown to be affected by factors such as muscle mass and nutrition, factors which have been demonstrated to affect creatinine values. In addition, a rise in creatinine does not become evident until the GFR has fallen by approximately 50%.
1. Grubb A. Diagnostic value of analysis of cystatin C and protein HC in biological fluids. Clin Nephrol. 1992; 38(Suppl 1):S20-7. PubMed 1284235
2. Coll E, Botey A, Alvarez L, et al. Serum cystatin C as a new marker for noninvasive estimation of glomerular filtration rate and as a marker for early renal impairment. Am J Kidney Dis. 2000; 36:29-34. PubMed 10873868
Collection Details:
Patient Preparation:
Overnight fasting is preferred.
Collection Instructions:
Red-top tube, gel-barrier tube, or green-top (heparin) tube.
Separate serum or plasma from red blood cells.
Room temperature.