Cobalt, Urine

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Category:

Turnaround Time: 2 - 4 days
CPT Code: 83018, 82570
Test Type: 5 mL Urine (random or 24-hour)
Stability Time:

Temperature

Period

Room temperature

14 days

Refrigerated

14 days

Frozen

14 days

Freeze/thaw cycles

Stable x3
Reference Range:

 

• Environmental exposure: 1.0−2.0 μg/L; <2.0 μg/g creatinine

• Occupational exposure: BEI® (sampling time is end of shift at end of work week): 15.0 μg/L1

Overview:

Monitor industrial exposure to cobalt.

This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.

1. TLVs and BEIs, Threshold Limit Values for Chemical Substances and Physical Agents and Biological Exposure Indices 2010, American Conference of Governmental Industrial Hygienists (ACGIH).

Collection Details:

Collection Instructions:

Do not use preservative. Preservatives used for routine analysis may contain mercuric oxide (ie, Stabilur), which interferes with all metal testing. If both urinalysis and metal testing are ordered, please submit a separate urine specimen (containing no additive) for the metal testing.

Plastic urine container, no preservative.

Sampling time is end of shift at end of work week. Metals with timing “end of shift at end of work week” (meaning four or five consecutive working days with exposure) are eliminated with half-lives longer than five hours. Such metals accumulate in the body during the work week; therefore, their timing is critical in relation to previous exposures.

Optional protocol: Instruct the patient to void at 8 AM and discard the specimen. Then collect all urine including the final specimen voided at the end of the 24-hour collection period (ie, 8 AM the next morning). Avoid contact with metal during collection. Screw the lid on securely.