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Register NowBehcet's Disease
Create a Free Account to View PricesTest Type: Kit Based, Buccal Swab
Overview:
Behçet’s disease is a systemic inflammatory vasculitis, characterized by a course of remission and relapse of oral ulcers, genital ulcers, skin lesions and ocular lesions. It can affect the arteries and veins of almost any system and has been shown to involve the gastrointestinal and neurological systems. The cause of Behçet’s is unknown but it is believed to be triggered by an infectious or environmental agent in a genetically predisposed individual.
Clinical Utility
The HLA class I molecule HLA-B51 is the most strongly associated risk factor and has been shown to be associated with Behçet’s in Turkish and Asian patients, though the association in Caucasian patients is much weaker. Testing for HLA-B51 is a useful, though not diagnostic, tool for Behçet’s as the vast majority of HLA-B51 carriers do not develop Behçet’s. Diagnosis is instead based on the recurrence of symptoms including oral ulcers, genital ulcers, skin lesions and ocular lesions. Treatment options depend on organs involved.
Collection Details:
Collection Instructions:
1. Please fill out all sections of the requisition form provided in your kit.
2. Rinse your mouth with cold water before you begin collecting your sample and then swallow to remove excess saliva.
3. Open one swab at a time and collect the sample by rubbing the swab on the inside of your cheek about 20 times or for 15-20 seconds in a circular motion. Swab firmly so that the cheek is pushed outward.
4. Dry the swab by shaking it in the air for 10-20 seconds.
5. Place the dried swab back in its original sleeve.
6. Use the other cheek for the next swabs. Repeat the same process for the rest of the swabs. Collect sample on all 3 swabs.
6. Place the swab sleeves containing the dry swabs and Requisition Form in the Kashi paper envelope included in the kit.
7. [Important] Sign and fill in your name and date of sample collection on the envelope.
8. Ship the test kit back to the laboratory using the shipping mailer provided.