AST and Platelets with APRI

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Category:

CPT Code:

84450; 85049

Test Type: 0.5 Ml (Serum)

Overview:

Use
AST to Platelet Ratio Index (APRI) is reported to be a simple, noninvasive, and readily available laboratory test index that can stratify patients with HCV and Non-Alcoholic Fatty Liver Disease (NAFLD) who are at high or low risk for significant fibrosis and cirrhosis with high degree of accuracy.

Limitations
Clumping may cause false low count. Platelet satellitism around neutrophils will cause a pseudothrombocytopenia. RBC or WBC fragments including fragmented fragile leucemic cells and neutrophil pseudoplatelets may cause falsely elevated counts.


Methodology
AST: kinetic; Platelet Count: automated cell counter

 

Collection Details:

Collection Instructions:

Specimen Requirements

Specimen

Serum and whole blood

Volume

0.5 mL (serum); fill tube to capacity (whole blood)

Minimum Volume

0.5 mL (serum), 0.5 mL (whole blood)

Container

Gel-barrier tube or red-top tube and lavender-top (EDTA) tube

Collection

Separate serum from cells within 45 minutes of collection; invert EDTA tube immediately 8 to 10 times once tube is filled at the time of collection.