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Overview:
Use: Anti-TIF-1gamma (P155) antibodies are present in 15-38% of adult DM and 20-30% in JDM. Highly associated with malignancy, which is found in 50-75% of positive adult patients; 89% specificity and 78% sensitivity for diagnosing cancer-associated DM; no cancer association in children.
Limitations: This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.
Methodology: Enzyme-linked immunosorbent assay (ELISA)
Collection Instructions:
Specimen: Serum
Volume: 1 mL
Minimum Volume: 0.5 mL (Note: This volume does not allow for repeat testing.)
Container: Red-top tube or gel-barrier tube
Collection: Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
Storage Instructions: Refrigerate or freeze.
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