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Overview:
Use: SRP is considered a Myositis-specific antibody. It is commonly found in Polymyositis, ILD and arthritis, and occasionally in dermatomyositis. Anti-SRP was first described in a polymyositis patient in 1986. Anti-SRP antibodies are rare, in only about 4% of myositis patients, and are often found in African American females with an acute, severe onset of polymyositis, with poor response to therapy.
Limitations: This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.
Methodology: RIPA gel radiography
Collection Instructions:
Specimen: Serum
Volume: 1 mL
Minimum Volume: 0.3 mL (Note: This volume does not allow for repeat testing.)
Container: Red-top tube or gel-barrier tube
Collection: Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
Storage Instructions: Refrigerate or freeze.
Stability Requirements: Room temperature 7 days
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