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Use: 14-3-3 eta protein is a joint-derived, proinflammatory mediator that is implicated in the joint erosion process and pathogenesis of RA. Serum 14-3-3 eta is elevated in both early and established RA.Limitations: This test was developed, and its performance characteristics w...
View Lab Test17-Hydroxyprogesterone (17-OHP) in urine is greatly elevated in patients with polycystic ovarian disease and in patients with idiopathic hirsutism.This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food...
View Lab Test17-Hydroxyprogesterone (17-OHP) in urine is greatly elevated in patients with polycystic ovarian disease and in patients with idiopathic hirsutism. Wong and coworkers showed that measurement of 17-OHP in 24-hour urine produced results that may be useful for monitoring gluco...
View Lab TestMarkedly elevated in patients with congenital adrenal hyperplasia;1-5 evaluate hirsutism and/or infertility;6 assess or rule out certain adrenal or ovarian tumors with endocrine activity7This test was developed and its performance characteristics determined by LabCo...
View Lab TestUse: Aromatic L-amino acid decarboxylase (AADC) is a pyridoxal 5'-phosphate dependent enzyme responsible for the formation of dopamine and serotonin. AADC deficiency is a congenital autosomal recessive metabolic disorder that causes hypotonia, hypokinesia, oculogyric crises...
View Lab TestUse: Plasma 5-hydroxy-indoleacetic acid (5HIAA or 5-HIAA) is a metabolite of serotonin that can be elevated as a result of carcinoid tumors/carcinoid syndrome.Limitations: This test was developed and its performance characteristics determined by LabCorp. It has not been cleared...
View Lab TestLevels of 5-HIAA may not be elevated in nonfunctional tumors. Because flushing is mediated by different hormones in foregut and midgut tumors, some patients with a neuroendocrine tumors will have symptoms of flushing with low or normal levels of 5-HIAA. A number of substanc...
View Lab TestA serotonin analysis is most frequently performed for the diagnosis of carcinoid tumors of the enterochromaffin (Kultschitzsky) cells of the small intestine. These tumor cells release large amounts of serotonin, which can produce the clinical syndrome of flushing, diarrhea...
View Lab TestUse: Test for the laboratory diagnosis of myasthenia gravis (MG)Limitations: This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration. In rare cases AChR antibodies can be found in p...
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